Euglena Gracilis (Chronodyn™)
-Cell Energizer
Function
Chronobiological cell energizer. Tones and firms the skin. Enhances skin vitality and fights against signs of fatigue.
Definition
Biotechnological extract of Euglena Gracilis
Properties
Triggers cell metabolism by stimulating calcium release and enhancing the energy level.
Characteristics
Euglena Gracilis, a unicellular pseudo algae, is a chronobiological (overnight synthesis) source of phosphoinositides - the origin of the mobilization of calcium and supply of ATP.
Applications
Euglena Gracilis (Chronodyn™) is recommended to apply at nighttime due to enhance cell metabolism during the skin's repair and energy production phase.
In Vitro Tests
Neosynthesis of IP3 (inositol triphoshate): Euglena Gracilis (Chronodyn™) added to culture medium of human keratinocytes / incubation period : 1 Minute
Neosynthesis of ATP: Euglena Gracilis (Chronodyn™) added to culture of normal human fibroblasts depleted in ATP / incubation period : 2 hours
Calcium release: Measurement of calcium released by keratinocytes incubated with 3% Euglena Gracilis (Chronodyn™) is determined by specific fluorescent labeling.
Euglena Gracilis (Chronodyn™) stimulates elements essential for metabolism, strengthening the skin’s ability to assure its regenerative function.
Neosynthesis of ATP: Euglena Gracilis (Chronodyn™) added to culture of normal human fibroblasts depleted in ATP / incubation period : 2 hours
Calcium release: Measurement of calcium released by keratinocytes incubated with 3% Euglena Gracilis (Chronodyn™) is determined by specific fluorescent labeling.
Euglena Gracilis (Chronodyn™) stimulates elements essential for metabolism, strengthening the skin’s ability to assure its regenerative function.
In vivo Tests
Double blind study: Twice daily application of a cream contain 3% Euglena Gracilis (Chronodyn™) applied to half face, against placebo on the other half for 28 days, on 21 female volunteers (average age: 44 years). Measurement of skin fatigue on creek with torque meter after 5 torsion.
Chronodyn™ increases skin firmness: After 4 weeks skin resists deformation: +21.3%.
Chronodyn™increases skin tone and vitality: After 2 weeks skin recuperates from deformation: +27.1%
After 28 days the skin is 3 times firmer and 4 times more toned than placebo treated site. Chronodyn™ strengthens skin's resistance to brush away the signs of age.
Chronodyn™ increases skin firmness: After 4 weeks skin resists deformation: +21.3%.
Chronodyn™increases skin tone and vitality: After 2 weeks skin recuperates from deformation: +27.1%
After 28 days the skin is 3 times firmer and 4 times more toned than placebo treated site. Chronodyn™ strengthens skin's resistance to brush away the signs of age.
