Estrogen Dominance in Men

Just in a women, men suffer the effects of Estrogen Dominance

Many researchers including John R. Lee, M.D (Leading pioneer in natural progesterone therapy), Dr. Jesse Hanley and Dr. Peter Eckhart are coming to the conclusion that the over abundance of estrogen and estrogen like substances (xenoestrogens or foreign estrogens) are responsible for a vast number of today's health problems. This over abundance of estrogen is referred to as estrogen dominance which is an increasingly serious problem for both women and men. Dr. Lee believes that it is excessive exposure to estrogen that is the primary cause of prostate enlargement and prostate cancer. Xenoestrogens in the environment are among the culprits. Sources of xenoestrogens includes commercially raised beef, chicken and pork, birth control pills, spermicide, detergent, plastics, plastic drinking bottles, pesticides, herbicides, personal care products, canned foods and lacquers.



Men produce estrogen (Estradiol) but in much lower amount than women. Men also produce progesterone, but about half the amount from that of females. Progesterone is made in men by the adrenal glands and testes. Progesterone is vital to good health in both women and men. It is the primary precursor of our adrenal cortical hormones and testosterone. The male hormone, testosterone, is an antagonist to estradiol (E2). It is made from progesterone. Men normally continue to produce relatively normal level of testosterone for their age and well into the seventies. Contrary to common perception, testosterone does not cause prostate cancer. Young men have high levels of testosterone and old men low levels. If testosterone were the cause of prostate cancer, young men would be dying of prostate cancer.

Studies had shown that men with the highest level of testosterone have the least prostate enlargement. Conversely, men with the highest level of estrogen have enlarged prostates. Declining testosterone from aging, together with increasing level of estrogen, is the most likely reason for prostate enlargement and cancer in men. The prostate is embryologically the same as the uterus in the female. Research Studies (Listed at the end of this newsletter) have shown that when prostate cells are exposed to estrogen, the cells proliferate and become cancerous. When progesterone or testosterone was added, cancer cell dies.

During the aging process, progesterone level falls in men, especially after age 60. Progesterone is the chief inhibitor of an enzyme called 5-alpha reductase that is responsible for converting testosterone to dihydrotestosterone (DHT), a much more potent derivative that is linked to prostate cancer. When the level of progesterone falls in men, the amount of conversion from testosterone to DHT increases. Unfortunately, DHT is not as powerful an inhibitor of cancer cell compared to testosterone. When the level of testosterone decreases, the relative level of estradiol in men increases. Estradiol, turns on BCL2 oncogene (Onco means cancer) and increases the risk of prostate cancer if adequate amount of progesterone is not there to counteract its effect by stimulating the P53 cancer protection gene.

Benign prostatic hyperplasia (BPH), a prostate enlargement condition, is a common condition affecting the majority of male above age 50. Prostate cancer is a leading cause of cancer in men. It is slow growing, with a doubling time of 5 years. Numerous anecdotal reports of reduction of BPH and reversal of prostate cancer through the use of natural progesterone supplementation have been reported.


Clinical Evidence

Dr. John Lee's women patients used natural progesterone for osteoporosis. Some of their spouses also used it for their bones and their prostate cancer went into remission. Dr. John Lee has had about 10 out of 10 men in remission from prostate cancer using Natural Progesterone cream. One man was being treated at Mayo Clinic for prostate cancer and it had spread to the bone. He began to use his wife's progesterone cream for his bones. After 6 months of progesterone cream applied to his skin,

Mayo Clinic could find no evidence of any prostate cancer. Several men with prostate cancer have told Dr. Lee that their PSA (Prostate Specific Antigen) level-decreased when they started using a daily dab of progesterone cream, and that they have had no progression of their prostate lesions. Dr. Peter Eckhart also had patients in remission from prostate cancer. Studies had shown that PSA level returns to normal upon application of natural progesterone cream before or after prostate surgery.

Dr. Lee reported twelve men who applied natural progesterone cream for their osteoporosis. All of them began to experience relief from their condition, after three months of daily massage, they were also experiencing an improved urine flow, with less pressure on their prostate glands and a noticeable decrease in nightly urination. Each patient was also suffering from enlarged prostates.


Ways to combat "Estrogen Dominance" in Men

Cut out the estrogen mimicking chemicals in our life
  • Use glass or ceramics whenever possible to store food
  • If you must use plastics, do not heat them up in the microwave oven or leave them in the sun.
  • Use a simple detergent with less chemicals
  • Use a simple soap
  • Use natural pest control not pesticides.
  • Avoid Synthetic Chemicals.
  • Don't use herbicides.
  • Buy hormone free meats to eat.
  • Buy "Organic" produce, produce grown without pesticides, herbicides or synthetic fertilizer
  • Use Condoms without spermicide for Birth control.