Astaxanthin Melanin

Astaxanthin Reduced Melanin Production 40%

Astaxanthin Melanin
Skin pigmentation such as stains and freckles are caused by excessive uneven production of melanin. It is known by reducing tyrosinase activity will reduce pigmentation. This can be achieved by inhibiting the synthesis of tyrosinase or by using an antagonist substrate for tyrosinase. Pigmentation is also prevented by inhibiting auto-oxidation of dopa and suppressing inflammatory reactions such as erythema following UV irradiation. Whitening agents such as Arbutin, Kojic Acid and Ascorbic acid derivative inhibit tyrosinase synthesis. The study was conducted the potential whitening effect of Astaxanthin relative to the other whitening agents.


melanin study
Astaxanthin dose-dependently reduced melanin deposition at concentrations between 2.5uM and 5 uM and 10uM. This action was stronger than of Arbutin, Kojic Acid and Ascorbic Acid derivatives. Astaxanthin did not inactivate isolated tyrosinase and this suggests the mechanism of melanin reduction of the autoxidation of dopa and dopaquinone.
Arakame K.
Superior Skin Protection via Astaxanthin Carotenoid Science, Vol.5, April, 2002


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